Technologies Used In Development Of Immuno protective Vaccines. BY December, 2001 flurry of mend: 1. Abstr human action....3 2. Introduction..3 2.1 What is Immunocontraception and why?...3 2.2 Â Â Â Â Â Â Â Â The zone Pellucida: as vaccine purport...5 2.3 Â Â Â Â Â Â Â Â Sperm surface antigens as vaccine target......5 2.4 Â Â Â Â Â Â Â Â Hormones as targets for vaccines..6 3. Methods and techniques.7 3.1 Antiserum doing.7 3.2 Adjuvants....9 3.3 speech communication sytems......10 3.4 ELISA...11 3.5 Immunoblotting (Western blotting)......12 3.6 Immunoelectrophoresis and Immunodiffusion..12 3.7 Radio immunochemical assay.14 4. Discussion...14 Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 5. References.....15 Abstract. The normal go on for individuals lack to control the number and time of pregnancy is by apply conventional contraceptives much(prenominal)(prenominal) as; The Pill, condo ms, surgical sterilization, injectable hormones and chemical spermicides, full to mention a few. Research institutions around the world be now canvass a new approach for despotic the process of fertilization. By utilizing and stimulating the soundboxs own insubordinate reaction, they argon making come up in the exploitation of anti-fertility vaccines, withal known as immunocontraceptives.
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The development of anti-fertility vaccines are not wholly envisaged for use in gentleman only, but will in addition be important in controlling wild heart populations, such as to limit the detrimental effects gent species have on their surroun dings. Â Â Â Â Â Â Â Â presently the! re are trey main approaches to the development of contraceptive vaccines, all of which aim to chip the bodys immune body to act against reproductive components. One approach is to induce an immune response against hormones controlling the development of the embryo, such as (hCG). The other two main approaches are the consequence of immunity against gamete-specific antigens found on the surface on sperm carrel or the zona pellucida (ZP), a glycoprotein layer that surrounds the egg cell (Aitken, R. J., et al, 1993). With other words, the immune system ability to recognize and fail self-molecules has to be reprogrammed/manipulated in such a way, to mount an immune response aimed at molecules the body normally tolerates. Â Â Â Â Â Â Â Â In this review, the main focus has been placed on some of the key laboratory... If you expect to get a exuberant essay, order it on our website:
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